What is thymosin alpha-1 (TA1 peptide)?
Most searches for thymosin alpha 1 dosage come from someone who wants to turn an amount into syringe units, and that is the math this page covers. Thymosin alpha-1 is a peptide of 28 amino acids, acetylated at its starting end. It was first isolated from thymus tissue as part of a group of peptides named thymosins after that gland. The synthetic version has the nonproprietary name thymalfasin, and supplier labels often shorten it to TA1 or ta1 peptide.
Despite the shared family name, thymosin alpha-1 is unrelated in structure to thymosin beta-4, a much larger protein. The two are separate compounds, sold separately. This page makes no statement about what thymosin alpha-1 does in the body.
How much BAC water for a thymosin alpha-1 vial?
Research vials are usually labeled thymosin alpha 1 5mg or 10 mg of freeze-dried powder. The mg in the vial is fixed; the volume of bacteriostatic water you add sets the concentration. The chart shows micrograms per unit on a U-100 syringe at common water volumes.
| BAC water | 5 mg vial | 10 mg vial |
|---|---|---|
| 1 mL | 50 mcg/unit 5 mg/mL | 100 mcg/unit 10 mg/mL |
| 2 mL | 25 mcg/unit 2.5 mg/mL | 50 mcg/unit 5 mg/mL |
| 3 mL | 16.67 mcg/unit 1.667 mg/mL | 33.33 mcg/unit 3.333 mg/mL |
| 5 mL | 10 mcg/unit 1 mg/mL | 20 mcg/unit 2 mg/mL |
Each cell shows mcg per unit on a U-100 syringe (100 units = 1 mL) and the resulting concentration.
Read across a row to compare the two vial sizes at the same volume, or down a column to see how the same vial thins out as water is added. Each cell is vial mg × 1,000 ÷ (water mL × 100). There is no single correct volume; one that divides evenly into the vial mg gives cleaner numbers. The BAC water to peptide ratio guide explains why the numbers move the way they do.
Worked example: thymosin alpha-1 reconstitution in units
The calculator runs three steps. Vial mg ÷ water mL gives the concentration. The amount you enter ÷ that concentration gives the volume in mL. Volume × 100 gives U-100 units. For example, if the amount you already have is 500 mcg, and a 5 mg thymosin alpha-1 vial is mixed with 2 mL of BAC water:
The math: 5 mg ÷ 2 mL = 2.5 mg/mL (2,500 mcg/mL), which is 25 mcg per unit. 500 mcg ÷ 2,500 mcg/mL = 0.2 mL = 20 units on a U-100 syringe.
That amount is an arbitrary figure picked because it comes out clean. It is not a suggestion. With a 10 mg vial, the same steps give a higher concentration and fewer units for the same amount:
The math: 10 mg ÷ 2 mL = 5 mg/mL (5,000 mcg/mL), which is 50 mcg per unit. 500 mcg ÷ 5,000 mcg/mL = 0.1 mL = 10 units on a U-100 syringe.
Keep everything in one unit before dividing: 1 mg = 1,000 mcg. The mg to mcg conversion guide has a quick reference.
Thymosin alpha 1 dosage calculator: what the numbers mean
A thymosin alpha 1 dosage calculator does one job: it tells you how many units on a U-100 syringe line up with an amount you already have, for your vial size and water volume. You bring the amount. The calculator returns a concentration, a volume in mL and a unit mark. It does not set, suggest or check a dose, a schedule or a frequency. Those come from product labeling and a qualified professional.
Units are the same size on every U-100 syringe: 100 units = 1 mL and 1 unit = 0.01 mL. A 0.3 mL or 0.5 mL syringe just holds fewer of them. If a result looks wrong, such as a tiny fraction of a unit, the usual cause is an mg and mcg mix-up. You can check the calculator math by hand with the same formula.
Thymosin alpha-1 reconstitution notes from suppliers
Supplier instructions vary, so the label on your vial comes first. Some suppliers specify bacteriostatic water; others list sterile water. Some product sheets say to add the water slowly down the side of the vial and swirl gently rather than shake, and many list refrigeration after mixing. Some supplier sheets give the 5 mg and 10 mg sizes different suggested volumes. That choice changes only the concentration; whatever volume you use, enter that exact figure in the calculator. For general steps, see the peptide reconstitution guide. Labels may also list thymalfasin as the ingredient name; the mg figure is what the calculator needs.
Is thymosin alpha-1 FDA-approved?
No. Thymosin alpha-1 is not FDA-approved in the United States. Thymalfasin has been approved in a number of other countries under the brand name Zadaxin, a finished pharmaceutical product with its own labeled strength. Research-labeled vials sold online are not that product and are labeled for research use only.
A correct calculation cannot confirm a vial’s identity, purity, sterility or stability. The calculator assumes the label is accurate, so treat any result as arithmetic, not as a statement that a product is safe or suitable for any use.
Thymosin Alpha-1 FAQ
How much BAC water do you add to a thymosin alpha 1 5mg vial?
There is no single required volume. The chart shows how 1, 2, 3 and 5 mL change the mcg per unit. Follow the product labeling for the diluent and volume, then enter the volume you used.
Does this page give a thymosin alpha 1 dosage?
No. It converts an amount you already have into mL and U-100 syringe units for your vial and water volume. It does not recommend a dose, schedule or frequency.
Is TA1 the same as thymosin alpha-1?
Yes. TA1 is a common abbreviation for thymosin alpha-1, and thymalfasin is the nonproprietary name of its synthetic form.
Is thymosin alpha-1 related to thymosin beta-4?
Only by name. Both were first found in thymus tissue, but they are different molecules of very different size and are sold as separate products.
Is thymosin alpha-1 FDA-approved?
No. It is not FDA-approved in the United States. Thymalfasin is approved in some other countries as Zadaxin, and research-labeled vials are not that product.