What is tesamorelin?
Searches for tesamorelin dosage usually come down to one practical question: how does a number turn into marks on a syringe? That arithmetic is what this page covers. Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH). It is built on the full 44-amino-acid GHRH sequence with a chemical group added at one end, which is what separates it from shorter GHRH fragments such as sermorelin.
Tesamorelin exists in two very different forms. One is an FDA-approved drug sold as Egrifta, with its own labeling. The other is research-labeled freeze-dried powder sold online, most often as tesamorelin 5mg or tesamorelin 10mg vials. This page deals only with the reconstitution math for research vials and does not describe what tesamorelin does in the body.
How much BAC water for a tesamorelin vial?
There is no single correct volume for tesamorelin reconstitution. The bacteriostatic water you add only sets the concentration: less water gives a stronger solution and fewer units for the same amount, more water gives a weaker solution and more units. The chart below shows mcg per unit for both common vial sizes.
| BAC water | 5 mg vial | 10 mg vial |
|---|---|---|
| 1 mL | 50 mcg/unit 5 mg/mL | 100 mcg/unit 10 mg/mL |
| 2 mL | 25 mcg/unit 2.5 mg/mL | 50 mcg/unit 5 mg/mL |
| 3 mL | 16.67 mcg/unit 1.667 mg/mL | 33.33 mcg/unit 3.333 mg/mL |
| 5 mL | 10 mcg/unit 1 mg/mL | 20 mcg/unit 2 mg/mL |
Each cell shows mcg per unit on a U-100 syringe (100 units = 1 mL) and the resulting concentration.
Read across a row to compare the two vial sizes at the same volume, or down a column to see how one vial changes as water is added. Each cell is vial mg × 1,000 ÷ (water mL × 100). The BAC water to peptide ratio guide explains why doubling the water halves every figure.
Worked example: tesamorelin 5mg and 10mg in units
Here is the arithmetic for one vial. For example, if the amount you already have is 500 mcg and a 5 mg tesamorelin vial is mixed with 2 mL of BAC water:
The math: 5 mg ÷ 2 mL = 2.5 mg/mL (2,500 mcg/mL), which is 25 mcg per unit. 500 mcg ÷ 2,500 mcg/mL = 0.2 mL = 20 units on a U-100 syringe.
The larger vial works the same way. For example, if the amount you already have is 1 mg and a 10 mg vial is mixed with 5 mL:
The math: 10 mg ÷ 5 mL = 2 mg/mL (2,000 mcg/mL), which is 20 mcg per unit. 1 mg ÷ 2,000 mcg/mL = 0.5 mL = 50 units on a U-100 syringe.
The method never changes. Divide the vial amount by the water volume for concentration, divide the amount you have by that concentration for mL, and multiply by 100 for units, since 100 units equal 1 mL on a U-100 syringe. Units are the same size on every U-100 syringe; only the capacity differs, as the syringe units to mL chart shows.
Notice what the two examples have in common. A bigger vial does not change the method, only the concentration. If you know the vial size, the water volume and the amount you already have, the unit mark follows directly, and changing any one of those three values changes the answer. That is why the calculator asks for all three before it shows a result.
Tesamorelin dosage calculator: what the numbers mean
A tesamorelin calculator, and the tesamorelin dosage chart above, answer a narrow question: how many units on a U-100 syringe match an amount you already have, for your vial and water volume. The calculator takes the mg on the label, the mL of BAC water and the amount you enter, and returns concentration, volume and a unit mark.
It does not choose an amount, a frequency or a schedule, and it cannot say whether a figure is appropriate or whether a research vial matches its label. Those questions belong to the product labeling and a qualified professional. A tesamorelin dosage chart built this way is a conversion table, not a protocol. If a result looks off, check for an mg and mcg mix-up first; the guide to checking calculator math shows how to verify any result by hand.
Tesamorelin reconstitution notes from suppliers and labeling
The approved product is packaged with its own diluent and its own labeled mixing instructions, and those instructions apply only to that product. Research vials are different: some suppliers specify bacteriostatic water and list a suggested volume, while others leave it open. Some suppliers advise swirling gently rather than shaking, since vigorous shaking can foam a peptide solution.
Whether a preserved or unpreserved diluent fits a given product is a labeling question, not a math one. The comparison of bacteriostatic and sterile water explains how the two differ.
Tesamorelin regulatory status
Tesamorelin is FDA-approved as Egrifta. That approval covers the labeled product only. Research-labeled tesamorelin vials sold online are not Egrifta, are not covered by its labeling, and are sold for research use only. A correct calculation cannot confirm identity, purity or sterility, so the numbers are only as reliable as the label they start from. Other research compounds with their own calculators are listed in the peptide library.
Tesamorelin FAQ
How much BAC water do you add to a 5 mg tesamorelin vial?
There is no single required volume. The water only sets the concentration. The chart shows mcg per unit for several volumes; the diluent and volume come from the product labeling.
Is this a tesamorelin dosage calculator?
It converts an amount you already have into mL and U-100 syringe units for your vial and water volume. It does not recommend a dose, schedule or treatment.
Is tesamorelin FDA-approved?
Yes, as Egrifta, a specific labeled product. Research-labeled tesamorelin vials sold online are not that product and are sold for research use only.
What changes between a 5 mg and a 10 mg tesamorelin vial?
With the same water volume, the 10 mg vial is twice as concentrated, so the same amount takes half as many units. The chart shows both sizes side by side.
How is tesamorelin different from sermorelin?
Both are GHRH analogues. Sermorelin is a shorter fragment of GHRH, while tesamorelin is built on the full-length sequence with a chemical group added. The calculator math is identical for both.