What is survodutide?
Most searches for survodutide dosage come from people who already have a vial and want to read it on a syringe, and that math is what this page covers. Survodutide is a synthetic peptide that activates two receptors: the glucagon receptor and the GLP-1 receptor. Compounds with that profile are called GLP-1/glucagon dual agonists. It was developed by Boehringer Ingelheim, which has studied it under the code BI 456906, originally in collaboration with Zealand Pharma.
Survodutide carries a fatty-acid side chain that lengthens how long the peptide stays in circulation, a design shared by several newer metabolic peptides. It has been studied in clinical trials in relation to body weight and liver health. This page makes no claims about effects in people. It does one job: the math of survodutide reconstitution with bacteriostatic water and reading the result on a U-100 syringe.
How much BAC water for a survodutide vial?
Research-labeled vials are usually sold as survodutide 10mg or 20 mg of freeze-dried powder. The mg in the vial stays fixed; the BAC water you add decides the concentration. The chart shows micrograms per unit on a U-100 syringe for common water volumes.
| BAC water | 10 mg vial | 20 mg vial |
|---|---|---|
| 1 mL | 100 mcg/unit 10 mg/mL | 200 mcg/unit 20 mg/mL |
| 2 mL | 50 mcg/unit 5 mg/mL | 100 mcg/unit 10 mg/mL |
| 3 mL | 33.33 mcg/unit 3.333 mg/mL | 66.67 mcg/unit 6.667 mg/mL |
| 4 mL | 25 mcg/unit 2.5 mg/mL | 50 mcg/unit 5 mg/mL |
| 5 mL | 20 mcg/unit 2 mg/mL | 40 mcg/unit 4 mg/mL |
Each cell shows mcg per unit on a U-100 syringe (100 units = 1 mL) and the resulting concentration.
Read across a row to compare the two vial sizes at the same water volume, or down a column to see how more water spreads the powder thinner. A 20 mg vial with 1 or 2 mL of water gives a strong concentration where a single unit carries a lot of peptide, so some people prefer a larger volume for easier reading. There is no single correct choice. The BAC water to peptide ratio guide explains how the chart is built.
Worked example: survodutide reconstitution in syringe units
The calculator follows three steps. Vial mg ÷ water mL gives the concentration. The amount you enter ÷ that concentration gives the volume in mL. Volume in mL × 100 gives U-100 units. For example, if the amount you already have is 2 mg, and the vial is a 20 mg vial with 4 mL of water added:
The math: 20 mg ÷ 4 mL = 5 mg/mL (5,000 mcg/mL), which is 50 mcg per unit. 2 mg ÷ 5,000 mcg/mL = 0.4 mL = 40 units on a U-100 syringe.
That amount is an arbitrary figure chosen because the result is easy to follow. It is not a suggestion. Survodutide amounts are usually written in milligrams, so make sure the calculator is set to mg rather than mcg; 1 mg = 1,000 mcg. The mg to mcg conversion guide walks through switching between the two.
Survodutide dosage calculator: what the numbers mean
The survodutide dosage calculator converts an amount you bring into mL and syringe units, based on your vial size and the water you actually added. It does not set, suggest or check a dose, a schedule, a titration or a frequency. Clinical trials use their own protocols, which this page does not reproduce; any survodutide dosage question belongs with product labeling and a qualified professional.
Units are the same size on every U-100 syringe: 100 units = 1 mL and 1 unit = 0.01 mL. Smaller 0.3 mL and 0.5 mL syringes simply hold fewer units. If a result needs more units than your syringe holds, the math is still correct; it just exceeds that syringe’s capacity. You can check the calculator math by hand if you want to confirm a result.
Survodutide vs mazdutide
Survodutide and mazdutide are easy to mix up: both are GLP-1/glucagon dual agonists with similar-sounding names. They are distinct molecules with different sequences and different developers. Survodutide comes from Boehringer Ingelheim; mazdutide was discovered at Eli Lilly and is developed by Innovent Biologics. Their vials are separate products, and a label for one tells you nothing about the other. Always select the compound and vial size printed on your own vial.
Survodutide reconstitution notes from suppliers
Supplier directions vary, so your vial’s label comes first. Some suppliers specify bacteriostatic water, others sterile water. Some product sheets say to add the water slowly down the side of the vial and swirl gently until clear rather than shaking, and many list separate storage temperatures before and after mixing. Some suggest a water volume per vial size; that choice only changes the concentration.
Enter the exact volume you used so the unit count matches what is in the vial. The calculator assumes the printed mg is accurate and cannot confirm a vial’s identity, purity or sterility.
Is survodutide FDA-approved?
No. Survodutide is an investigational compound and is not FDA-approved. Research-labeled vials sold online are not an approved medicine, and there is no labeled product with set strengths to compare them against. The only numbers you can rely on are the mg printed on the vial and the water you measured. Treat every result here as arithmetic, not as a statement that a product is safe or suitable for any use.
Survodutide FAQ
How much BAC water do you add to survodutide 10mg?
There is no single required volume. The chart shows how 1 to 5 mL change the micrograms per unit. Follow the product labeling for the diluent and volume, then enter the volume you used in the calculator.
Does this page give a survodutide dosage?
No. It converts an amount you already have into mL and U-100 syringe units for your vial size and water volume. It does not recommend a dose, schedule, titration or frequency.
Is survodutide the same as mazdutide?
No. Both act on the GLP-1 and glucagon receptors, but they are different molecules from different developers and are sold as separate products.
What is BI 456906?
BI 456906 is the development code Boehringer Ingelheim used for survodutide. Both names refer to the same compound.
Can I use the calculator for a survodutide 20mg vial?
Yes. Enter 20 mg as the vial size and the water volume you added, and the calculator works out the concentration and units the same way.