What is the SS-31 peptide?
The SS-31 peptide is a synthetic tetrapeptide, a chain of just four amino acids. Its name comes from the Szeto-Schiller series of peptides in which it was developed. The same molecule is known by the generic name elamipretide and by the earlier development codes MTP-131 and Bendavia, which is why supplier labels and search results use several different names for one compound.
Its sequence is D-Arg-Dmt-Lys-Phe-NH2, where Dmt is 2′,6′-dimethyltyrosine and the chain is amidated at the end. The alternating positive charges and aromatic groups are what researchers associate with its attraction to the inner mitochondrial membrane. This page makes no claims about effects in people. It handles one task: the math of ss-31 reconstitution with bacteriostatic water and reading the result on a U-100 syringe.
How much BAC water for an SS-31 vial?
Research vials are most often labeled ss 31 10mg or ss 31 50mg of freeze-dried powder. The mg in the vial is fixed; the BAC water you add sets the concentration. The chart shows micrograms per unit on a U-100 syringe for common water volumes.
| BAC water | 10 mg vial | 50 mg vial |
|---|---|---|
| 1 mL | 100 mcg/unit 10 mg/mL | 500 mcg/unit 50 mg/mL |
| 2 mL | 50 mcg/unit 5 mg/mL | 250 mcg/unit 25 mg/mL |
| 3 mL | 33.33 mcg/unit 3.333 mg/mL | 166.67 mcg/unit 16.667 mg/mL |
| 5 mL | 20 mcg/unit 2 mg/mL | 100 mcg/unit 10 mg/mL |
Each cell shows mcg per unit on a U-100 syringe (100 units = 1 mL) and the resulting concentration.
Read across a row to compare the two vial sizes at the same volume, or down a column to see how adding water spreads the same powder thinner. The 50 mg vial is five times the mass of the 10 mg vial, so at the same water volume every unit carries five times as much. There is no single correct volume; one that divides evenly into the vial mg gives cleaner numbers. For the principle behind the chart, see how the BAC water to peptide ratio works.
Worked example: SS-31 reconstitution in syringe units
The calculator runs three steps. Vial mg ÷ water mL gives the concentration. The amount you enter ÷ that concentration gives the volume in mL. Volume in mL × 100 gives U-100 units. For example, if the amount you already have is 1 mg, and the vial is 10 mg with 2 mL of water added:
The math: 10 mg ÷ 2 mL = 5 mg/mL (5,000 mcg/mL), which is 50 mcg per unit. 1 mg ÷ 5,000 mcg/mL = 0.2 mL = 20 units on a U-100 syringe.
That amount is arbitrary, chosen because it comes out clean, and it is not a suggestion. The same steps apply to a 50 mg vial; only the concentration changes. Because 1 mg = 1,000 mcg, make sure the unit you type matches the unit selected in the calculator. The U-100 syringe units to mL chart shows how units map to volume.
SS-31 peptide dosage calculator: what the numbers mean
People searching for SS-31 peptide dosage usually want to match an amount to the marks on a syringe. That is what this page does. You bring the amount; the calculator converts it into mL and units using your vial size and the water you actually added. It does not set, suggest or check a dose, a schedule or a frequency for SS-31 or elamipretide, and nothing here should be read that way. Those decisions belong to product labeling and a qualified professional.
Units are the same size on every U-100 syringe: 100 units = 1 mL and 1 unit = 0.01 mL. A 0.3 mL or 0.5 mL syringe holds fewer units but reads the same scale. If a result looks wrong, check the calculator math by hand with the same formula.
SS-31 reconstitution notes from suppliers
SS-31 is a short, water-soluble peptide, and supplier instructions for it are usually simple, but they are not identical, so the label on your vial comes first. Some suppliers specify bacteriostatic water; others list sterile water. Some product sheets ask for the water to run gently down the inside wall of the vial and for the vial to be swirled rather than shaken, and some give separate storage temperatures for the dry powder and the mixed solution.
Whichever volume you use, enter that exact figure in the calculator so the units match what is actually in the vial. The peptide reconstitution guide covers the general steps in more detail.
Elamipretide regulatory status
Elamipretide has been developed clinically by Stealth BioTherapeutics, and in 2025 it received FDA accelerated approval under the brand name Forzinity. That approval covers that specific labeled product. Research-labeled SS-31 vials sold online are not Forzinity, are not made or labeled to the same standard, and are sold for research use only.
A correct calculation cannot confirm a research vial’s identity, purity, sterility or stability. The calculator assumes the mg on the label is accurate. Treat every result as arithmetic, not as a statement that a product is safe or suitable for any use.
SS-31 (Elamipretide) FAQ
Is SS-31 the same as elamipretide?
Yes. SS-31 is the original research name and elamipretide is the generic name of the same four-amino-acid peptide. It has also been called MTP-131 and Bendavia.
How much BAC water do you add to SS-31 10mg?
There is no single required volume. The chart shows how 1, 2, 3 and 5 mL change the micrograms per unit. Follow the product labeling for the diluent and volume, then enter the volume you used in the calculator.
Does this page give an SS-31 dosage?
No. It converts an amount you already have into mL and U-100 syringe units for your vial and water volume. It does not recommend a dose, schedule or frequency.
Can I use the calculator for SS-31 50mg?
Yes. Enter 50 mg as the vial size and the water volume you added, and the calculator works out the concentration and units the same way as for a 10 mg vial.
Is a research SS-31 vial the same as the approved product?
No. The approved elamipretide product is a specific labeled drug. Research-labeled SS-31 vials are separate products sold for research use only.